Prolozone Injection Therapy Q&A
Prolozone injections are a regenerative therapy designed to treat joint pain and soft tissue injuries. This non-invasive treatment supports the body’s natural healing processes, offering relief from chronic pain and improving overall function. Visit Dr. Jason Zabell, and his team to learn more about how Prolozone injections can support your recovery. For more information, contact us or request an appointment online. We are conveniently located at 4900 SE Division St. Portland, OR 97206.


Table of Contents:
How does Prolozone injection therapy differ from traditional cortisone injections?
Is Prolozone injection therapy effective for joint pain and soft tissue injuries?
What should I expect during and after a Prolozone injection therapy session?
Is Prolozone injection therapy a long-term solution for pain management?
At Urban Wellness Group, our approach to treating joint pain and inflammation emphasizes natural, regenerative solutions that align with our commitment to holistic, patient-centered care. Two commonly discussed injection therapies—Prolozone injections and traditional cortisone injections—differ significantly in their philosophy, methodology, and long-term outcomes.
Prolozone therapy, an advanced regenerative treatment we offer at Urban Wellness Group, involves injecting a therapeutic blend of ozone gas, oxygen, vitamins, minerals, and occasionally gentle homeopathic remedies directly into painful or injured joints and tissues. This unique combination stimulates the body’s innate healing abilities by enhancing circulation, oxygenation, nutrient delivery, and cellular repair processes. By targeting the root cause of pain and inflammation, Prolozone therapy supports lasting tissue regeneration and joint health, aligning seamlessly with our integrative wellness philosophy.
Conversely, traditional cortisone injections rely on corticosteroids—potent anti-inflammatory medications—to quickly suppress inflammation and temporarily ease pain symptoms. While cortisone injections offer fast relief, they do not address the underlying cause of pain and inflammation and do not promote natural tissue regeneration. Over time, repeated cortisone injections can potentially weaken ligaments, tendons, and cartilage, potentially causing further deterioration and limiting long-term joint health.
At Urban Wellness Group, we prioritize treatments that encourage the body’s natural healing capacity and support lasting wellness. While cortisone injections may have a place for quick symptom management, we believe regenerative therapies like Prolozone offer a more sustainable, holistic solution. By promoting genuine healing, improving joint function, and addressing the root causes of discomfort, Prolozone injection therapy aligns closely with our mission to help patients achieve long-term wellness and vibrant health.
At Urban Wellness Group, we offer Prolozone injection therapy, a minimally invasive regenerative treatment designed to alleviate joint pain, reduce inflammation, and promote healing in soft tissue injuries. Prolozone therapy involves injecting a mixture of ozone gas, vitamins, nutrients, and sometimes homeopathic remedies directly into affected joints or tissues, activating the body’s natural healing processes.
This therapy helps improve oxygen utilization, reduce inflammation, and foster tissue repair, offering a holistic path to wellness. Patients with chronic joint pain, arthritis, tendonitis, ligament sprains, or soft tissue injuries often report significant relief, improved mobility, and decreased pain, allowing them to return to daily activities with greater ease.
Although clinical evidence supporting Prolozone therapy is promising, further research is needed to fully confirm its long-term efficacy and safety. At Urban Wellness Group, we prioritize staying updated on the latest advancements in regenerative medicine to offer evidence-informed care.
We recommend a detailed consultation with our specialists to determine if Prolozone therapy is right for you, ensuring a personalized approach that aligns with your health goals.
When you schedule your visit with Urban Wellness Group, your practitioner will begin by thoroughly reviewing your medical history, discussing your symptoms and wellness goals, and conducting a careful physical assessment of the affected area. This comprehensive evaluation ensures that Prolozone therapy aligns well with your individual needs and health objectives.
During your Prolozone session, you’ll be comfortably positioned in a relaxing, supportive environment. Our skilled practitioner will meticulously cleanse and sterilize the targeted area, prioritizing your comfort, safety, and overall experience. Using a fine, precision needle, we gently inject a specialized therapeutic mixture containing ozone gas combined with restorative nutrients such as vitamins, minerals, and natural anti-inflammatory agents directly into the affected tissues. You may experience slight pressure or mild discomfort during this brief procedure, but most patients find the sensation tolerable and fleeting.
After your Prolozone injection, it’s normal to experience mild soreness, tenderness, or stiffness at the injection site for a brief period, typically lasting from a few hours up to a few days. Urban Wellness Group practitioners will advise you on effective self-care strategies—such as gentle stretching, rest, or applying ice or heat—to minimize any temporary discomfort and support your healing process. Most of our patients comfortably resume their everyday activities within one or two days, though we may recommend temporarily avoiding strenuous activities to maximize therapeutic benefits.
While some individuals notice significant improvement shortly after their initial session, others may benefit from a series of treatments to achieve optimal results. Our dedicated practitioners will closely monitor your progress and collaboratively adjust your treatment plan to ensure continued improvement and satisfaction.
Your comfort, safety, and wellness are our top priorities. If you have any questions, concerns, or unexpected symptoms after your treatment, we encourage you to contact our team at Urban Wellness Group promptly.
Prolozone therapy combines ozone gas with targeted nutrients and natural anti-inflammatory substances, creating a powerful therapeutic blend. By stimulating the body’s own healing mechanisms, this treatment helps enhance oxygenation, reduce inflammation, and encourage tissue repair at the source of pain.
Our clinical experience shows that many patients experience significant reductions in pain and improved functionality following Prolozone therapy. Rather than merely masking symptoms, Prolozone addresses the underlying factors contributing to chronic discomfort by promoting tissue regeneration, improved circulation, and enhanced oxygen delivery.
The long-term effectiveness of Prolozone injections can vary based on individual health conditions, the severity of tissue damage, age, lifestyle, and the patient’s overall engagement with complementary therapies and rehabilitation exercises. Many of our patients report sustained relief lasting months or even years following a series of treatments, while others choose periodic maintenance injections to maintain optimal well-being.
While anecdotal and clinical experiences are highly promising, the broader medical literature continues to advocate for more comprehensive studies to further confirm Prolozone’s long-term effectiveness. At Urban Wellness Group, our integrative medical professionals are committed to staying informed about the latest research and providing evidence-based, personalized care.
If you’re considering Prolozone therapy as part of your holistic pain management plan, we invite you to visit Urban Wellness Group for a personalized consultation. Our experienced practitioners will assess your unique needs, answer your questions, and help determine whether Prolozone therapy aligns with your long-term health and wellness goals. For more information, contact us or request an appointment online. We serve patients from Portland OR, Milwaukie OR, Happy Valley OR, Oak Grove OR, Lake Oswego OR, Beaverton OR, Tigard OR, and surrounding areas.

Additional Services You May Need
▸ Hyperbaric Oxygen Therapy
▸ Ozone Therapy
▸ Bio-identical Hormone Therapy
▸ IV Therapy
▸ Auto Injury Treatment
▸ Shockwave Therapy
▸ Work Injuries Treatment
▸ Regenerative Medicine
▸ Acupuncture
▸ Prolozone Injection Therapy
▸ Chinese Medicine
▸ Natural Medicine
▸ Cancer Care
▸ Spinal Alignment

Additional Services You May Need
▸ Hyperbaric Oxygen Therapy
▸ Ozone Therapy
▸ Bio-identical Hormone Therapy
▸ IV Therapy
▸ Auto Injury Treatment
▸ Shockwave Therapy
▸ Work Injuries Treatment
▸ Regenerative Medicine
▸ Acupuncture
▸ Prolozone Injection Therapy
▸ Chinese Medicine
▸ Natural Medicine
▸ Cancer Care
▸ Spinal Alignment